All Articles
Browse every published article, from the latest research to earlier analysis. Use the page numbers below to explore the complete archive.
Does 400 mg of Caffeine Improve Vigilance Across the Menstrual Cycle? What a 12-Athlete Pilot Actually Shows
A 12-athlete caffeine crossover found better vigilance and simple reaction time but no significant reaction-time phase interaction or endurance benefit. Read the measured limits.
Does Daily Caffeine Worsen Working Memory Without Changing Task-Load fMRI? A 20-Man Crossover Trial
A 20-man randomized crossover found worse 3-back performance with daily caffeine and withdrawal, but no change in task-load fMRI. Saliva testing was not a blood impairment test.
Does Caffeine Prevent Attention Lapses After 26 Hours Awake? A 24-Person Trial Found a Benefit—and a Task-Fatigue Limit
A 24-person blinded crossover trial found caffeine reduced some vigilance deficits after 26 hours awake, but not the within-task rise in lapses or executive-task errors.
Can One Session of iTBS Improve Visual Memory in Methamphetamine Recovery? A 17-Man Sham-Controlled Study
A 17-man sham-controlled iTBS study found less visual orientation error after one session, but a nonsignificant fifth-session group contrast. Separate modeled capacity improved.
Can Heart-Rate Variability Predict Stimulant-Related Creativity Gains in ADHD? A 17-Adult Pilot
In a 17-adult ADHD pilot, pNN50 did not predict stimulant-related anagram changes; exploratory HRV-creativity links failed multiplicity correction. No blood drug assay.
Why Did Methylphenidate Improve Math Productivity Without Better Working Memory? A 63-Child Crossover Study
A 63-child ADHD crossover found improved math productivity without significant gains on tested working-memory or motivation measures; parent-rated competence partly mediated output.
Can D-Amphetamine Improve Zebrafish Maze Alternation While Reducing Flexibility? A 36-Fish Study
In 36 allocated zebrafish, d-amphetamine increased Y-maze alternation after repeated exposure but reduced flexibility and movement. No blood drug concentrations or human impairment were measured.
Does D-Amphetamine Increase Motivation Without Changing EEG Alpha Power? A Human–Mouse Experiment
What 23 adults and two separate mouse cohorts reveal about oral or injected amphetamine, progressive-ratio persistence, EEG alpha null findings and forensic limits.
Does Methylphenidate Help People Remember Words Later Without Improving Immediate Learning? A 19-Man Crossover Study
Original n18 adult ADHD crossover: delayed word recall improved before CES-D adjustment, lost statistical significance afterward. Genuine nulls and forensic limits.
Can Placebo Improve an Objective ADHD Attention Test? A 40-Adult Methylphenidate Crossover Trial
A 40-adult randomized crossover trial found QbInattention improved with placebo and 20 mg methylphenidate; impulsivity drug-v-placebo was nonsignificant.
Can Plasma Dexamphetamine or Zolpidem Predict Attention? A 60-Man Controlled Trial
A 60-man trial measured dexamphetamine and zolpidem in separated plasma. Some attention outcomes changed, but no blood-level prediction of individual impairment was shown.
Can a Four-Week Cognitive Training App Improve Methamphetamine Decision-Making Without Changing Drug-Cue Attention? A 40-Person Trial
Original 40-man randomized CCAT trial: laboratory learning and gambling-task changes, null methamphetamine Stroop interaction, and limits for blood-drug and impairment claims.
Does 10 mg Methylphenidate Improve Visual Attention? A 25-Person Trial Found Better Number Memory, Not Better Eye Scanning
A 25-person methylphenidate placebo crossover improved number-memory accuracy, not eye scanning. No measured blood level or published driving outcome.
Do Methamphetamine Cues Disrupt Conflict Adaptation? A 44-Man Simon Task Study
A 44-man primary Simon-task study found cue-specific response interference and weaker conflict adaptation, not measured blood methamphetamine or DUI impairment.
Can an fMRI Scan Prove Methamphetamine Impairment After Abstinence? What 54 Men’s Brain Networks Actually Showed
A 54-man methamphetamine abstinence fMRI study found MoCA and hippocampal connectivity differences, but no drug blood levels, driving test, or personal impairment validation.
Does Modafinil Improve Difficult Working-Memory Tests but Not Creativity? A 64-Adult Trial
In 64 healthy adults, 200 mg oral modafinil improved demanding spatial memory, planning and delayed recognition, but not broad creativity. No blood assay or driving test.
Do Methamphetamine Users Link Gambling Rewards to Mood Differently? What 76 Men Actually Showed
Original 76-man study: methamphetamine-use history changed optimal gambling choices and fitted mood weights, but not uncertainty choice or individual impairment.
Can Modafinil Preserve Vigilance During a 29-Hour Wake Shift Without Making People Feel Less Sleepy? An 18-Person Trial
Primary 18-person forced-desynchrony trial: modafinil improved selected vigilance trajectories and reduced sleep epochs, but subjective sleepiness was unchanged.
Do Methylphenidate and Lisdexamfetamine Differ in 15-Hour Simulated Driving? A 44-Adult Crossover Trial
A 44-adult ADHD crossover found PRC-063 noninferior to lisdexamfetamine on virtual driving through 15 hours—not proof of safe driving or whole-blood drug levels.
Does Modafinil Slow Verbal Responses Without Improving Accuracy? What a Randomized Hayling Test Found
In a 2014 randomized trial, 200 mg modafinil slowed verbal Hayling responses without reducing errors. Understand the 61-person analysis and forensic limits.
Does Modafinil Reduce Persistent Fatigue After Stroke? What a 36-Person MIDAS Crossover Trial Proved—and Did Not Prove
A 36-person crossover study found six-week modafinil improved self-rated fatigue after stroke, while overall cognition and mood remained nonsignificant. No drug blood levels or driving test.
Does Methamphetamine Cue-Avoidance Training Prevent Relapse? A 24-Patient Pilot Found No Significant Benefit and Important Safety Concerns
A randomized methamphetamine cue-avoidance pilot found no significant abstinence benefit in 24 patients; eight experienced distress or craving reactions.
Do Boys Respond Better to Racemic Amphetamine? What Classroom Scores in 97 Children Actually Showed
A 97-child crossover trial found stronger 2-hour SKAMP differences in boys, but not math-performance sex interactions or measured blood amphetamine. Review real limits.
Does Dextroamphetamine Shift Effort Choices Most When Reward Is Unlikely? A 17-Adult Trial
An original human placebo-controlled crossover illustrates a stimulant effect on probabilistic effort choices, not a forensic blood-drug or personal driving test.
Can Brain Connectivity Distinguish LSD, MDMA, and d-Amphetamine in One Person? What a 25-Volunteer fMRI Trial Shows
A 25-person crossover fMRI study found different LSD, MDMA and d-amphetamine brain-network effects, but no validated scan-based drug or impairment test.
Does Modafinil Reliably Improve Vigilance in Sleep-Deprived Pilots? What an 11-Person Crossover Study Actually Shows
An original 11-pilot modafinil crossover reported better overnight PVT reaction time but different RT and sleepiness ICCs. No measured blood drug level or flight-safety validation.
Does 200 mg of Caffeine Make Drivers React Faster? A 100-Driver Trial Found Faster Simulated Braking but No Less Lane Weaving
A randomized 100-driver caffeine trial found faster simulated braking (p=.048), not steadier lane keeping (p=.75). Plasma HPLC results and forensic limits.
Can 800 mg of Caffeine Prevent Dangerous Attention Lapses After 77 Hours Awake? What a 23-Person Trial Found
In a 23-person, 77-hour sleep-loss trial, 800 mg/night caffeine reduced some vigilance lapses but not all ten-second nonresponses. Learn the forensic limits.
Can Eye Tracking Identify Methamphetamine Cue Bias Without Measuring Intoxication? A 66-Man Study
What 30 methamphetamine-history men and 36 controls showed in eye tracking, dot-probe testing and craving—and why it does not prove intoxication.
Does Methamphetamine Use Disorder Predict Less Trust and More Punishment? What 102 Adults’ Tasks Showed
In 102 retained adults, methamphetamine use disorder was associated with differences in happy-face recognition, trustee repayments and simulated punishment—not proven violence or individual intoxication.