All Articles
Browse every published article, from the latest research to earlier analysis. Use the page numbers below to explore the complete archive.
Does Harder Exercise Increase Brain Oxygenation During Methamphetamine Recovery? Why an 18-Person fNIRS Study Did Not Clear Statistical Correction
In 18 men recovering from methamphetamine dependence, higher-intensity cycling raised fNIRS signal trends—but corrected left-DLPFC p=.066 and connectivity p=.20 were not significant.
Does a Lisdexamfetamine Oral Solution Match Capsules in Plasma? A 29-Volunteer Study
A 29-adult crossover compares lisdexamfetamine solution with capsules using measured plasma prodrug and dexamfetamine, highlighting limits for forensic interpretation.
Does Low-Dose Amphetamine Improve Attention Only in Poor Performers? What 18 Rats and Striatal Chemistry Show
A 2017 rat study found 0.1 mg/kg d-amphetamine improved low-baseline visual-signal accuracy; brain HVA, 5-HIAA and DAT results cannot predict human impairment.
Does Methamphetamine Dependence Weaken Reactive More Than Proactive Control? A 178-Person AX-CPT Study
A 178-person AX-CPT study found lower reactive-control scores in men with methamphetamine dependence but nonsignificant proactive contrasts. What can it prove?
Does 20 mg Dextroamphetamine Reduce Late-Task Reaction-Time Instability? A 69-Person Conners CPT Trial
In 69 adults, 20 mg dextroamphetamine changed late-task reaction-time error (p=.003) while aggregate accuracy, gambling and card sorting remained nonsignificant.
Does Acute Methamphetamine Change Mouse Memory and 36,376 Hippocampal Nuclei? What the 2026 Experiment Actually Shows
A 2026 mouse methamphetamine experiment found memory-task differences and 619 gene changes in 36,376 hippocampal nuclei—not a human blood impairment test.
Can Methamphetamine Narrow Driving Gaze Without Increasing Lane Weaving? A 20-Driver Alcohol Crossover
In a 20-driver crossover, oral methamphetamine changed gaze entropy while alcohol increased simulated lane weaving. Read the whole-blood and null evidence.
Can Amphetamine Delay Exhaustion While Hiding Muscle Heat? A 12-Rat Treadmill Study
In 12 rats, d-amphetamine delayed treadmill exhaustion and slowed measured core warming, while a model predicted hotter muscle. See results and limits.
Does Oral Methamphetamine Speed Reactions More in Women Than Men? What 73 Volunteers Actually Showed
A 73-person placebo-controlled oral methamphetamine study found faster monetary-cue reactions in women but not men. No measured blood level or driving impairment was established.
Does Oral d-Methamphetamine Impair Simulated Driving? Why a 20-Person Trial Found a Slower Emergency Speed but No Significant Overall Deficit
In 20 adults, oral d-methamphetamine did not significantly change overall simulator errors; one emergency-speed contrast was nominal. Blood vs saliva evidence and DUI limits.
Does 700 mg of CBD Cause Sedation or Reduce Cortical Excitability? A 25-Man Crossover Trial
A controlled 25-man trial measured CBD in plasma after 30 and 700 mg. Most cortical excitability and psychomotor outcomes were nonsignificant.
Can Amphetamine Improve Vigilance Without Improving Response Inhibition? A 24-Person Crossover Trial
A controlled 24-person study found amphetamine drugs improved vigilance and go accuracy, not stop-signal inhibition. Plasma amphetamine is not an impairment cutoff.
How Long Does Oral CBD Persist in Calf Plasma—and Can Seven Calves Establish a Cattle Withdrawal Time?
A seven-calf primary study measured plasma CBD after one 5 mg/kg oral oil dose. Examine peak, 23-hour estimated half-life, variability, and why meat or milk withdrawal remains untested.
Can THC in Breath Aerosols Prove Recent Cannabis Use? An 18-Person Impaction-Filter Study
A primary 18-person, 42-sample pilot detected breath-aerosol THC in 80% after cannabis use but also at baseline. Why no individual recent-use or impairment cutoff follows.
Can a Forehead Brain Scan Prove THC Impairment? What 128 Participants Showed
A 128-person randomized THC-placebo crossover study found disrupted prefrontal fNIRS connectivity, but did not validate a roadside impairment test or measure blood THC.
Does a Cannabis Breathalyzer Miss THC Vapor? Measured Pressure Versus Modeled Breath Fractions
Direct THC/CBD/CBN vapor-pressure measurements and modeled breath aerosol fractions show why particle-only THC breath capture needs validation—not proof of impairment.
Can a Positive Urine THC Test After a Negative Mean New Cannabis Use? Evidence From 60 Monitored Users
A 60-person monitored-abstinence study found urine THC screening can turn positive after negative. Learn why THC-COOH, creatinine, and cutoffs matter.
Can Finger-Prick Blood Measure CBD Like Venous Blood or Plasma? A Five-Patient VAMS Study
Can a 30-µL finger-prick test measure CBD? Five Dravet patients, capillary-versus-venous results, assay limits and why p = 0.69 is not equivalence.
Can Cannabis Edibles and 0.05% Breath Alcohol Impair Driving When Field Sobriety Tests Are Negative? A 25-Person Trial
A 25-person crossover trial found greater simulator driving changes after edible THC plus 0.05% breath alcohol, often without significant sobriety-test changes.
Can a Carbon-Paste Electrode Detect THC in Saliva? Practical Versus Theoretical Limits
A 2015 THC electrode experiment detected 0.50 µM in synthetic saliva—not people. See why theoretical nanomolar buffer limits cannot prove roadside accuracy.
Does Oral CBD Turn Into THC in the Stomach? What a Three-Minipig Study Actually Measured
Three minipigs received oral CBD. Plasma and gut THC and 11-OH-THC stayed below assay limits. Learn what that means—and does not prove—for forensic tests.
Can Urine Fluorescence Identify THC Without GC–MS? Four Cannabinoids, One Small Validation Study
Can urine fluorescence identify THC? A primary 2023 study of four analytes reveals spectral overlap, mixed-model LOQs, and limits of a four-donor validation.
Can CBD Reduce Virus-Triggered Seizures at Two Hours but Not Nine? The TMEV Mouse Evidence
In TMEV-infected mice, CBD 150 mg/kg reduced observed seizures two hours after injection, not nine hours. Read the primary study, safety signals and limits.
Does Acute Cold Stress Release Stored THC Into Plasma? A 15-Person Study
A primary cold-water immersion study in 15 cannabis users found higher glycerol and fatty acids but no significant rise in plasma THC. Matrices, tasks and limits explained.
Can a Smartphone Detect Slower Movement After Cannabis Concentrates When Plasma THC Poorly Predicts It? A 65-User Study
A 65-user cannabis concentrate study found slower arm and leg movement and acute sway changes, but tapping nulls and weak plasma THC correlations cannot diagnose impairment.
Do CBD–THC Nanoemulsions Delay Seizures Without Restoring Memory? Two PTZ Mouse Models
Short answer: In a 2025 experiment using male Swiss mice, oral nanoemulsions containing cannabidiol (CBD), delta-9-tetrahydrocannabinol (THC), or a 1:1 combination improved selected seizure outcomes after chemically induced challenges. In a repeated-challenge experiment, CBD at 10 mg/kg and CBD–THC combinations at 1.5 or 3 mg/kg delayed severe seizure development, but the 6 mg/kg combination did…
Can Whole-Blood THC Exceed 5 ng/mL Days After Cannabis Use Without Worse Simulator Driving? A 190-Person Study
In 190 frequent cannabis users, 10 had whole-blood THC ≥5 ng/mL after requested abstinence. Simulator cutpoints did not separate groups in 187 users.
Does Oral THC Reduce Willingness to Work for Rewards? A Controlled Study of 58 Women
A controlled 58-woman study found 15 mg oral THC reduced difficult-task choices, but 7.5 mg was nonsignificant. Separate motivation, motor speed, and blood testing.
Does Smoked Cannabis Cause Aversive Effects in People at Psychosis Risk? What a 12-Person Placebo Study Found
A 12-person placebo study found aversive ratings and selective digit-copy changes after smoked cannabis, but Go/No-Go postdose and N-Back results were null.
Does CYP2C9*3 Lower THC-COOH Without Lowering Plasma THC? Evidence From 66 Driving Cases
In 66 men’s DUID cases, CYP2C9*3 tracked lower plasma THC-COOH, but parent THC was not significantly different. Original GC-MS and forensic limits.