All Articles
Browse every published article, from the latest research to earlier analysis. Use the page numbers below to explore the complete archive.
Can Cognitive Tests Predict Methamphetamine Treatment Response? A 53-Person Study and the Correction That Changes the Answer
In a 30-patient methamphetamine contingency-management pilot plus 23 controls, adjusted Trail Making performance differed by response, while CPT lost significance after correction.
Does Methylphenidate Improve Attention Through Brain-State Changes? A 37-Person PET and fMRI Trial
A 37-person methylphenidate PET/fMRI trial found better 2-ball accuracy (p=.023), but not 3-ball accuracy or mean response speed. Imaging is not a blood assay.
Did Dexamphetamine Improve Inhibitory Control in 47 Adults with Obesity? The Null Treatment Interaction
A randomized dexamphetamine obesity study found no treatment-specific improvement in stop-signal inhibition or executive-function ratings. Understand n=47 and why p=.039 does not settle causation.
Does Stopping d-Amphetamine Increase Methamphetamine Craving? What a 34-Person Residential Trial Actually Tested
A 34-person residential trial found more craving after switching from supervised d-amphetamine to placebo. See the real outcomes, nulls, and forensic limits.
Does Caffeine Speed Reactions by Improving Attention Rather Than Motor Speed? An EEG Study of 15 Women
In a 15-woman caffeine crossover, reactions were faster and stimulus-locked P3b timing mediated about one-third of the modeled effect; blood caffeine and driving were not tested.
Does Methamphetamine Dependence Affect Digit-Order Memory Without Slowing Responses? Evidence From 121 Adults
A 121-adult study found lower accuracy for mentally reordered digits, but no group-specific reaction-time difference. What it does—and does not—prove.
Can a FAAH Gene Variant Predict How Amphetamine Feels? What 159 Volunteers Actually Showed
A 159-person study linked some FAAH variants to self-reported arousal and fatigue after 10 mg d-amphetamine; why this cannot predict blood levels or DUI impairment.
Can Attention Lapses Predict D-Amphetamine Liking? Why Two Impulsivity Tests Pointed in Opposite Directions in 165 Adults
A 165-person controlled study found opposite associations for baseline attention lapses and stop-signal inhibition with oral d-amphetamine liking. What it cannot prove.
Does Working-Memory Training Improve Inhibition in Abstinent Methamphetamine Users? A 32-Patient Trial
A 32-patient trial found n-back and running-memory improvements but no significant Stroop, go/no-go, flanker or task-switching benefit.
Does Adolescent Methylmercury Exposure Alter Adult Amphetamine Responses? Evidence From 30 Rats
Short answer: A controlled study of 30 male rats found that adult d-amphetamine disrupted visual-signal detection and short-term remembering, but adolescent methylmercury exposure did not independently produce a clear deficit on these particular measures. The strongest statistical model of the drug-challenge hit-rate data depended on the delay before a response and the administered amphetamine dose,…
Does Reporting Stimulants With Antidepressants Prove a Drug Interaction? A 1,976-Student Survey
A primary study of student reports shows stimulant and depression-prescription overlap but no blood drug assays or verified serotonin toxicity. Source-based forensic limits.
Do Caffeine and Modafinil Protect Working Memory Differently After 36 Hours Awake? A 14-Person EEG Study
In 14 men, modafinil and caffeine produced different two-back accuracy and P2/LPC EEG patterns after 36 hours awake, but reaction time was not significantly changed; no blood levels or driving were measured.
Does Dextroamphetamine Improve Cognitive Control—or Just Change EEG Signals? A 23-Person Masked Attention Trial
A randomized 23-adult dextroamphetamine study found faster task responses, stronger frontal P3a and an easy-task theta decrease—but no significant overall P3b or blood drug measurement.
Does D-Amphetamine Raise Psychosis-Like Ratings Without Improving Memory? Two 20-Person Drug Trials
Two independent 20-person blinded stimulant trials found no span-memory benefit; d-amphetamine elevated psychosis-like ratings. No whole-blood drug assay.
Can a Wearable Sweat Patch Detect Methamphetamine and Cocaine? What a CRISPR Prototype Actually Tested
A 2024 CRISPR/Cas12a wearable sweat-patch experiment tested prepared methamphetamine and cocaine solutions—not confirmed human impairment or blood drug levels.
Can a Methamphetamine-Word EEG Signal Distinguish Psychosis History? An Addiction Stroop Study of 68 People
Original 68-person methamphetamine-word Stroop study: left-anterior N200 differences, null behavioral/P300/N450 tests, and why EEG cannot diagnose individual intoxication.
Did Tai Chi Improve Inhibition or Preserve Memory in Women Recovering From Methamphetamine Use? A 72-Person Trial
A trial in 72 women found both exercise groups improved No-Go accuracy; 3-back declined overall and switching was nonsignificant. No drug assay or DUI proof.
Can Decaffeinated Coffee Increase Alertness Without the Vigilance Effects of Regular Coffee? A 59-Adult Crossover Study
A 59-adult coffee trial found decaf raised reported alertness while regular coffee improved select vigilance tests. Saliva caffeine is not blood impairment.
Can 10 mg of Dexamphetamine Offset Alcohol-Impaired Driving? What a 16-Driver Simulator Study Actually Found
A 16-person crossover study tested dexamphetamine and alcohol: simulated lane weaving, crossings, collisions, breath-estimated BAC and measured venous stimulant.
Does Repeated Dextroamphetamine Change Reward Processing Without Faster Decisions? A 22-Man fMRI Study
Original 22-man trial: repeated dextroamphetamine altered caudate and amygdala fMRI signals without drug-specific gains in gambling-task reaction speed.
Does Modafinil Outlast Caffeine for Overnight Aircrew Vigilance? A 32-Person Plasma Study
A 32-person aircrew crossover compared oral modafinil and caffeine using measured plasma, vigilance lapses and tracking. What improved—and what did not?
Can Gut Bacteria Intensify Amphetamine’s Effects? What Fly Dopamine and Butyrate Experiments Actually Show
Primary fly experiments link Fusobacterium nucleatum, butyrate, HDAC1 and dopamine transport to amphetamine responses—not human blood levels or legal impairment.
Can Neurofeedback Plus Swimming Reduce Methamphetamine Cue Craving? A 32-Man EEG Trial
What a four-arm trial of 32 men found about neurofeedback, swimming, EEG delta/alpha ratios and cue-induced craving—and what it cannot prove about intoxication.
Does Tai Chi Reduce Methamphetamine Cue Bias More Than Running? Evidence From 44 Men
In 44 men in methamphetamine rehabilitation, Tai Chi lowered a drug-cue bias score and choice reaction time versus running, but not craving. Source-based limits.
Can Exercise Reduce Methamphetamine-Cue Attention Bias? What a 63-Woman Dance-versus-Cycling Trial Measured
A 63-woman rehabilitation trial compared 12 weeks of dance and cycling on drug-cue attention and EEG. We separate actual improvements from nonsignificant ERP results and unmeasured blood drugs.
Can Dextroamphetamine Improve Target Detection in Both People and Mice? A 71-Adult, 32-Mouse Study
Primary 2018 research: dextroamphetamine improved 5-choice target detection in 71 adults and 32 mice, but not every response measure or driver impairment.
Can Resting EEG Microstates Identify Cognitive Differences in Methamphetamine Use Disorder? An 82-Person Study
An original study compared resting EEG microstates in 55 adults with methamphetamine use disorder and 27 controls. Review cognitive results, real nulls, and forensic limits.
Does Caffeine Speed Attention at Rest but Not During Exercise? A 24-Person Crossover Study
A 24-man crossover found caffeine sped task responses only at rest among moderate consumers; cycling sped responses but increased errors. No blood caffeine or driving test.
Does Amphetamine Increase Motivation Without Proving Better Cognition? What an 18-Mouse Touchscreen Experiment Measured
A 2015 18-mouse touchscreen study found higher reward effort after amphetamine, lower breakpoints with D2 antagonists, and important motor controls.
Can Caffeine Preserve Overnight Vigilance Without Improving Live-Fire Decisions? A 20-Soldier Trial
A 20-soldier trial found that caffeine gum improved overnight vigilance and reasoning speed, but not live-fire friend–foe accuracy. Read the forensic limits.