All Articles
Browse every published article, from the latest research to earlier analysis. Use the page numbers below to explore the complete archive.
Did Working-Memory Training Change Basal Ganglia Volume During Methamphetamine Treatment? A 66-Man MRI Cohort
A 2016 methamphetamine-treatment MRI study found putamen and cerebellum interactions but no significant direct CT-versus-usual-care follow-up volume difference. No forensic whole-blood drug assay.
Can a 140-mg Lisdexamfetamine Pilot Establish Cocaine Abstinence? What 17 Enrolled Adults Actually Showed
A 17-person, open-label cocaine-use pilot tested lisdexamfetamine up to 140 mg. Learn what tolerability and self-reported changes show—and cannot prove.
Does a 13-Hour Classroom Effect Prove Amphetamine Remains in Blood? A 99-Child Oral-Suspension Trial
An original 99-child oral amphetamine suspension trial found classroom effects at 1–13 hours. It did not measure forensic blood amphetamine concentrations.
Why Did Weekly Sweat Patches Miss Opiates More Often Than Cocaine? A 63-Patient Urine Comparison
Among 63 patients, only 188 of 536 sweat patches were valid. Opiate patch agreement was 27/81 versus cocaine 33/36 urine positives. Read the forensic limits.
Does Dextroamphetamine Increase Memory Intrusions Without Improving Correct Recall? A 31-Person Study
A 31-person oral dextroamphetamine experiment found more memory intrusions and word false alarms without stronger correct recall. Findings and forensic limits.
Does a Larger Putamen Mean Better Inhibition in Active Methamphetamine Dependence? A 37-Person MRI Study
In 37 adults, right putamen enlargement survived MRI correction, but other brain changes did not. Why this does not prove drug dose, individual impairment or causation.
Do ADHD Stimulants Prevent Sleepiness After 25 Hours Awake? What a 59-Man Study Measured
Primary 2026 study: 59 men, 25 hours awake, hourly Karolinska sleepiness; true significant and null results, no measured stimulant blood levels or driving safety test.
Does Oppositional Defiant Disorder Change Attention After Methylphenidate? A 53-Child Study
In 53 children with ADHD, reaction-time patterns differed after a single oral methylphenidate dose by ODD diagnosis—but there was no placebo or forensic blood assay.
Does Intravenous Methamphetamine Make People Jump to Conclusions? What a 17-Person Crossover Experiment Found
A 17-person IV methamphetamine crossover found mild psychotic-like symptoms but no significant beads-task decision effect; no blood-drug assay or DUI test.
Does Methylphenidate Compress Brain Networks? What 58 Adults and 4,958 Children Actually Showed
A 2026 primary study tested 60 mg methylphenidate in 38 and 20 adults, linking gradient compression to NET maps and visual attention; no forensic blood-drug assay.
Do Amphetamine and THC Change Emotional Memories More Than Neutral Memories? A 48-Person Recognition Experiment
Original 48-person photo-recognition analysis: oral dextroamphetamine improved recognition, THC impaired it, but formal emotional-valence interactions were nonsignificant. No eyewitness or forensic blood-level inference.
Can Modafinil or Galantamine Restore Simulator Flying After 27 Hours Awake? A 12-Person Crossover Study
A 12-man crossover flight-simulator study found limited modafinil and galantamine effects after prolonged wakefulness. Read the significant and null results and forensic limits.
Did a Smartphone Treatment Reduce Methamphetamine Use? What a 100-Person Trial Actually Measured
A 100-person methamphetamine smartphone trial reported lower cue craving within the app arm but did not establish drug-use reduction by toxicology; key missing-data and forensic limits.
Does Brain Stimulation Reduce Methamphetamine Craving? A 60-Man Trial Changed fMRI Connectivity, Not Craving
A 60-man triple-blind methamphetamine tDCS study showed corrected fMRI connectivity but no better craving relief than sham. Five activation clusters failed FDR.
Does Methamphetamine Picture-Stroop Bias Track Withdrawal Craving More Than VR Cue Craving? A 134-Man Study
A 134-man methamphetamine picture-Stroop study shows a 34.68-ms drug-picture delay and withdrawal-craving association; VR cue craving misses corrected and adjusted thresholds. No blood toxicology or DUI finding.
Do Stimulants Change Arousal and Reward Networks More Than Attention Networks? An MRI Analysis of 5,795 Children
In 5,795 children, same-day stimulant use tracked motor/arousal and salience connectivity, not corrected attention-network differences; five adults validated MRI directions. No blood drug assay.
Does Theta-Burst Stimulation Change Brain GABA in Methamphetamine Use Disorder? The 50-Person Interaction Test
A randomized 50-person study found no significant iTBS-specific GABA/NAA or Glx/NAA interaction, despite changes in craving and verbal learning.
Did 400 mg of Modafinil Reduce Methamphetamine Use? Why Urine Tests and Self-Reports Disagreed in a Seven-Person Pilot
A 2009 modafinil pilot enrolled 8, treated 7 and retained 4. Self-reported meth use declined, but repeated urine amphetamine screens did not: p=.61.
Does Dexamphetamine Improve Brain-Tumor Fatigue? A 41-Patient Trial Found No Benefit but More Psychiatric Events
A randomized primary-brain-tumor trial found no significant dexamphetamine fatigue benefit (p=.17), but more psychiatric adverse events (p=.018).
Does a Dextroamphetamine Patch Work Within One Hour? A 106-Child Crossover Trial
Original 106-child dextroamphetamine patch study: one-hour math results nonsignificant, two-to-twelve-hour classroom benefit; no measured forensic blood drug.
Do Current Methamphetamine Users Drive Differently When Blood Levels Do Not Predict Their Simulator Performance? A 30-Driver Study
In a 30-driver study, current methamphetamine users sped and wove more on a simulator, but blood methamphetamine levels did not predict key measures.
Can Amphetamine Raise VO₂max Yet Fail to Extend Exercise in Heat? Three Rat Experiments
Rat d-amphetamine increased VO₂max at 2 mg/kg, not running economy; at 32°C only 1 mg/kg extended endurance, while both raised terminal core temperature.
Can Theta-Burst Stimulation Reduce Methamphetamine Cue Craving? What a 57-Man Trial Found—and Why Its Prediction Scores Need Caution
A 57-man iTBS trial found lower methamphetamine cue-craving ratings and mixed executive-function changes. Its ROC intervals contain reporting errors; no forensic blood drug assay.
Did 10 or 15 mg Extended-Release Methylphenidate Outperform Placebo in Children With ADHD? A 221-Child Trial
In a pediatric methylphenidate trial, 20 and 40 mg beat placebo on ADHD ratings; 10 and 15 mg did not. Learn why ratings cannot establish blood drug levels or impaired driving.
Can Cocaine Remain Detectable in Newly Collected Hair Four Months After Reported Abstinence? A 15-Patient Study
In a 15-patient cohort, cocaine remained measurable in scalp hair for some at four months of reported abstinence; learn assay limits and why hair cannot date a use.
Why Can Methamphetamine-Dependent Adults Show Similar Average Stop Times but Weaker Neural Error Updating? A 96-Person fMRI Study
A 96-person fMRI study found real differences in modeled surprise and stop-error adjustment but no significant mean stop-time gap. No forensic blood drug levels.
Can Aerobic Exercise Change Blood-Based Neural Injury Markers During Methamphetamine Recovery? A 56-Person Trial
A 56-person methamphetamine-recovery trial found significant plasma NfL and serum NSE changes after exercise, but serum S100B was nonsignificant. What the blood assays really establish.
Does Early Methamphetamine Abstinence Affect Inhibitory Control but Not Laboratory Risk Taking? A 56-Person Study
A 56-person study found Stroop and stop-signal differences during early methamphetamine abstinence, but no significant gambling or balloon risk-task differences.
Does a Stronger Amphetamine Response Predict Heavy Drinking? What 192 Adults Actually Showed
What 192 adults actually showed about oral d-amphetamine ratings, negative emotionality and retrospective alcohol use. Distinguishes significant interactions, nulls and unmeasured blood drug levels.
Do Active Methamphetamine Users Discount Future, Past, Uncertain, and Other People’s Rewards Differently? A 65-Person Study
A 65-adult methamphetamine study compared future, past, probability, and social reward discounting; several subtests were null, and no blood-drug level was quantified.