All Articles
Browse every published article, from the latest research to earlier analysis. Use the page numbers below to explore the complete archive.
Does a Single Binge Change White Blood Cell Stiffness? What RT-DC Actually Measured
A 2023 alcohol-challenge pilot found no significant resting leukocyte stiffness change but differing cell counts and activated-cell responses. Learn the forensic limits.
Can a Camera-Verified Remote Breath Test Prove Continuous Abstinence? A 2023 Treatment Study
A 2023 randomized treatment study shows what camera-verified remote breath checks can and cannot establish about alcohol, missed tests, motivation and legal proof.
Can an fNIRS Brain Scan Prove Alcohol Impairment?
A 48-person alcohol challenge links Go/No-go performance with fNIRS brain asymmetry—but optical signals cannot prove an individual’s BAC or impairment.
Can Alcohol Impair the Decision to Stop Without Slowing a Stop Signal?
A controlled alcohol study found less voluntary stopping without general slowing on a stop-signal task. What can forensic experts actually infer?
Does Total Body Water Predict Breath Alcohol Better Than Body Surface Area? A 77-Person Study
In a 77-person study, total body water predicted modeled breath alcohol better than body surface area. Learn what was measured, estimated, and not proved.
Can a Negative Postmortem Cartilage Alcohol Test Rule Out Drinking?
A 2026 study shows why delayed negative ethanol results in rib and disc cartilage cannot rule out alcohol at death. Compare storage effects and limits.
Can a Rapid Hair Drug Screen Miss Cocaine or Misidentify THC? A 2026 Validation Study
A 2026 SAMElife hair-screening study found 11 THC screen positives without GC-MS confirmation and 4 missed cocaine positives. Learn the limitations.
Does Dextroamphetamine Change Task-Specific Brain Blood Flow Without Raising Global Flow? An Eight-Person PET Experiment
What eight healthy adults showed after oral dextroamphetamine: two PET task-specific regional signals, Raven accuracy, global blood-flow nulls and serum—not whole blood.
Does Methamphetamine Use Disorder Reduce Directed Exploration? A 114-Person Decision Experiment With an Anxiety Test
A 114-person methamphetamine-use-disorder study found lower directed exploration and learning rates, but genuine null effects of induced anxiety. What the research cannot prove for a forensic case.
Does 10 mg Methylphenidate Reduce Highway Lane Weaving Without Changing Gaze Entropy? A 25-Driver Crossover
Original 25-driver 10 mg methylphenidate crossover: lane SDLP and speed stability differed, while gaze entropy stayed nonsignificant in n19.
Can a Dopamine Transporter Gene Change How Amphetamine Feels? Evidence From 152 Volunteers
152 adults took oral d-amphetamine or placebo. An SLC6A3 marker was linked to self-reported stimulation, but objective genotype tests were null. No drug blood level was measured.
Does VMAT2 PET Show Dopamine Neuron Loss in Early Methamphetamine Abstinence? What a 33-Person Study Actually Measured
Original 33-person PET study: VMAT2 radiotracer binding rose in 16 methamphetamine users, especially five recent users. Why imaging cannot prove blood drug levels, neuron counts, or impairment.
Can Methylphenidate Improve Conscious Error Awareness Without Improving Inhibition? Evidence From 27 Men
In 27 healthy men, 30 mg methylphenidate increased awareness of errors while overall no-go inhibition was nonsignificant. Examine atomoxetine, fMRI and forensic limits.
Can Executive-Function Complaints and Quality of Life Predict Adult ADHD Stimulant Response? A 36-Patient Study
A 36-adult ADHD study linked BRIEF-A and quality-of-life scores to stimulant response. Read the real odds ratios, null results, and blood-testing limits.
Did Disulfiram Reduce Cocaine-Positive Urine Tests? What a 49-Patient Methadone Trial Actually Found
A 49-patient randomized methadone trial found 250/375 mg disulfiram slopes differed from placebo, but within-arm declines were not significant.
Can Reward Prediction Errors Explain Learning Differences in Methamphetamine-Use History? A 168-Person Study
In 168 adults, age-adjusted reward-error and learning interactions differed by gender, while recognition moderation was null. The study did not assay blood methamphetamine.
Does Early Methamphetamine Abstinence Change Brain Structure Without Detectable Myelin Loss? Evidence From 27 Adults
In 27 adults, early methamphetamine abstinence was associated with selected MRI cortical and Tower of London differences, but synthetic myelin results were nonsignificant. No forensic drug blood levels were measured.
Did Methamphetamine Patients Improve Cognition as Much as Other Addiction Patients? A 110-Person Inpatient Study
In 110 addiction inpatients, cognition improved in followed patients without a meth-specific change advantage; dropout difference p=.44. Forensic limitations.
Did Dextroamphetamine and Methamphetamine Change Brain Glutamate Differently? A 26-Volunteer MRS Study
In 24 analyzable MRS volunteers, 20 mg dextroamphetamine changed dACC glutamate, Glx and creatine; methamphetamine had no overall MRS effect. No whole-blood drug levels were tested.
Can Cocaine Be Detected on Public Touch Surfaces Without Proving Anyone Used It? A 45-Surface Survey
A 45-surface cocaine-screening survey found 35 DrugWipe positives. Learn why unconfirmed environmental immunoassays do not prove ingestion, transfer or blood cocaine.
Can Evening Methamphetamine Disrupt Sleep and Next-Day Cognitive Flexibility? Evidence From Five Rhesus Monkeys
Primary five-monkey study: evening 0.56 mg/kg methamphetamine changed actigraphy sleep and next-day task errors; lower dose sleep tests and omissions were nonsignificant. Not human blood evidence.
Does 20 mg Dextroamphetamine Reduce Post-Error Slowing Without Improving Accuracy? What 55 Volunteers Showed
An original 55-person N-back analysis found 20 mg d-amphetamine reduced post-error reaction time without significantly improving accuracy or measuring blood drug levels.
Does Methamphetamine Dependence Affect Remembering Future Intentions? A 65-Adult Prospective-Memory Study
A 65-adult study found more missed or mistimed future intentions with methamphetamine-dependence history, but recognition, delayed call and cue interaction were null.
Can External Cocaine Rubbed Into Hair Survive Shampooing Yet Fail a Wash-Criterion Test?
A primary cocaine hair-contamination study found measurable drug after shampooing but negative combined wash criteria. See the method, numeric hair results and limits.
Can Resting-State fMRI Predict Methamphetamine Craving After Treatment? The 82-Patient Study and Its 60% Accuracy Limit
Primary 2026 fMRI study: 82 methamphetamine patients, r=0.33 prediction of craving improvement, only 60% binary accuracy, marked sex imbalance; no blood assay or verified relapse.
Does Childhood Physical Neglect Predict Methamphetamine-Positive Urine Tests? Evidence From 115 Outpatients
Physical neglect and positive methamphetamine urine screens in 115 outpatients: what WCST results, study attrition and adjusted null findings actually establish.
Does a Longer Methamphetamine Use History Predict Cognitive Impairment? A 100-Adult Study
An original 100-adult study found group cognitive differences but no reliable link between self-reported methamphetamine amounts and individual impairment.
Does Methamphetamine Dependence Lead People to Reject Long-Term Gains After Short-Term Losses? Evidence From 89 Adults
An 89-person primary study found greater aversive pruning in methamphetamine use disorder but null general planning and reward sensitivity differences. No blood-drug test or DUI inference.
Can Inconsistent Reaction Times Predict Simulated Driving Problems in Methamphetamine Dependence? A 90-Man Study
Primary 90-man methamphetamine study: reaction-time variability predicts simulated penalties but direct crash-ticket group comparison p=.07, no blood drug assay.
What Did Preschool Lisdexamfetamine Actually Measure in Plasma? A 24-Child Study With Eight PK Profiles
A 24-child open-label preschool ADHD trial included 8 plasma PK profiles. See measured d-amphetamine concentrations, adverse events, and whole-blood limits.