All Articles
Browse every published article, from the latest research to earlier analysis. Use the page numbers below to explore the complete archive.
Why Eye-Movement Slowing Does Not Measure Every Sedative Drug Effect
Drug effects do not move together on a single scale. An eye-movement measurement can change without a matching change in balance or perceived alertness. That distinction matters when interpreting laboratory evidence of central nervous system drug activity. A study of pharmacodynamic profiles Chen and colleagues pooled data from five controlled studies in healthy volunteers. Their…
Can an Amphetamine Liquid Improve Classroom Ratings Before Math Performance? An 18-Child Crossover Trial
A primary 18-child crossover: 30-minute amphetamine suspension SKAMP ratings improved, but math tasks did not significantly differ from placebo until three hours.
Does D-Amphetamine Raise Cortical “Up-State” Activity—and Why Did Prazosin Block It in Rats?
A 126-rat study found baseline-dependent cortical electrical responses to IV d-amphetamine. Examine D1/D2 blockers, prazosin, nulls and forensic limits.
Does CBD Reduce Adult Epilepsy Seizures While Causing Drowsiness or Liver-Test Changes? A 37-Patient Study
What 37 adults with severe epilepsy showed: CBD seizure responders, 27% drowsiness, 19% abnormal liver tests, and limits of causal inference.
Does a Child’s Positive Urine CBD Metabolite Prove THC Exposure or Behavioral Harm? An 81-Pair Study
A primary 81-pair study detected CBD metabolites—not THC—in age-five child urine. See the behavior and cognition findings and why causation remains unproved.
Can Equal Alcohol Doses Yield Different Blood Alcohol Peaks in Beer, Wine and Vodka? A 15-Man Trial
In 15 fasting men given equal ethanol doses, whole-blood GC peaks averaged 50.3 mg/dL after beer, 61.7 after wine, and 77.4 after vodka/tonic. See forensic limits.
Can Moderate Alcohol Reduce Visual Memory Before Working Memory? A 154-Student Study
A 154-person study found different visual and working-memory results across alcoholmeter bands. Why breath readings and test centiles do not prove witness accuracy.
Can Postmortem Vitreous Alcohol Replace Blood BAC? What 31 Paired Samples Actually Show
A 2020 forensic study compared 31 postmortem blood and vitreous ethanol cases. Learn why strong correlation does not prove an individual BAC.
Can Gas-Tight Syringe Headspace GC-FID Quantify BAC Near a Legal Cutoff? What an 11-Batch Validation Shows
An 11-batch dual-column gas-tight syringe HS-GC-FID study measured 3.64% expanded uncertainty at 80 mg/100 mL. See calibration, LOQ, bias and forensic limits.
Can a Five-Minute GC–MS Run Reliably Quantify Whole-Blood Ethanol? A 2014 Validation Study
A 2014 whole-blood HS-GC–MS validation measured ethanol with n-propanol. See calibration, precision, storage data and forensic limits.
After a Four-Day Drinking Festival, Can Faster Attention Responses Hide More Errors? A 13-Person Pilot
A 13-person festival pilot found faster but less accurate Flankers responses at 0.00% breath alcohol. Examine sleep confounding, mixed tasks and forensic limits.
Can EtG or PEth Be Positive With Negative Blood Alcohol? 1,149 Samples
A 1,149-sample study found far more blood EtG and PEth positives than reportable plasma ethanol. Learn matrix differences and the forensic limits.
Can a 210-Calorie Protein–Fiber Snack Cut a Breath-Estimated Alcohol Peak? A Crossover Trial
A 21-person crossover trial found different breath-estimated alcohol peaks after equal-calorie snacks. What the study cannot prove about blood BAC or impairment.
Can Feeling Sober Prove You Were Below the Alcohol Driving Limit? A 90-Person SAFE Trial
A 90-person SAFE trial compared perceived sobriety and paired breath alcohol. Learn what the 39% and 53% underestimation figures do—and do not—prove in DUI cases.
Can PEth Verify a 14-Day Drinking History? A Two-Year Clinical Study
A two-year AUD-treatment study compared PEth with 14-day drinking diaries. Learn what a 0.22 µmol/L cutoff, sensitivity and imperfect agreement can prove.
Can Headspace GC-FID Quantify Vitreous Ethanol Reliably? A 2025 Validation Study’s Limits
A 2025 vitreous ethanol HS-GC-FID study reported a 0.15–2.50 mg/mL range and 3.60% analytical uncertainty—not proof of antemortem BAC or impairment.
Can Urine Sorbitol or an NMR Fingerprint Time Alcohol Use? A Crossover Study’s Limits
A 20-person crossover study found urine metabolite changes after alcohol. Learn why sorbitol and NMR fingerprints cannot prove BAC or drinking time.
Can Normal Pointing Hide Alcohol-Impaired Stopping? An Automatic-Correction Experiment
A controlled alcohol study found more action slips when participants had to stop a corrective reach, despite little detected change in automatic redirection. What it does—and does not—prove.
Can Passing One Cognitive Test Exclude Alcohol Impairment? A Six-Test Dose Study
A 56-person dose-response study found alcohol affected cognitive tests differently at ~0.048% breath-reported BAC. Learn what normal scores cannot prove.
Can a BAC Below 0.15‰ Be Back-Calculated? Limits of a New 43-Minute Rule
A 2026 study proposes a 43-minute correction for BAC below 0.15‰. See its evidence, sample sizes, analytical limits, and forensic uncertainty.
Can Repeat Alcohol Tests Give Different Pharmacokinetic Estimates? Breath, Blood and Urine Explained
A controlled repeat-dose study explains why breath and venous blood can yield different ethanol kinetic estimates—and why model precision is not a DUI BAC prediction interval.
Can Low Alcohol and a Memory Task Worsen Real-Highway Lane Keeping in Novice Drivers?
A controlled on-road alcohol trial measured lane keeping and auditory recall in novice and experienced drivers. What do BAC estimates and SDLP actually prove?
Can a Frozen Plasma Alcohol Retest Be Trusted After Five Months? An 80-Driver Study
Does freezing preserve plasma ethanol for a DUI retest? An 80-driver study at -20 °C found decreases after 2–5 months, with critical forensic limits.
Does Feeling Less Drunk Predict a Lower Measured BAC? A 20-Person Alcohol Challenge
Feeling less drunk does not prove lower BAC. Examine a 20-man alcohol challenge, self-rated sensitivity, measured BAC and first-pass metabolism limits.
Can a Congener Test Verify Drinking After a Crash? What Serum GC-MS Validation Proves
A 2021 serum HS-GC-MS study validated ethanol and congener measurement—not a clock for post-crash drinking. Review detection limits, precision and forensic limits.
Can a Blood EtG/EtS Ratio Date the Last Drink? Study Limits
Can a blood EtG/EtS ratio date a last drink? A 26-person study found a group-mean timing fit, not a validated personal forensic clock.
Can Low Blood Alcohol in a Drowning Be Postmortem Fermentation? A 967-Case Study
A 967-case drowning study found four low-positive blood ethanol results with negative urine. Learn what postmortem fermentation evidence can—and cannot—prove.
Can PEth Form After Blood Collection? Why a Dried Blood Spot Is Not Always Artifact-Free
Can PEth form after a blood draw? A 2021 LC-MS/MS study found PEth artifacts in wet blood and some dried-blood devices, but not open filter cards.
Can One Alcohol Binge Change Neutrophils Without Detectable Gut Leakage?
A 15-person alcohol-binge study changed neutrophil assay results without detected gut leakage or microbiome shift. Learn what it cannot prove.
Does High-Sulphite Wine Change Driving at the Same Alcohol Dose? A 2026 Simulator Study
A 32-driver simulator study compared wines with 86 versus 126 mg/L sulphites. Learn which driving outcomes changed and why BAC and causation remain uncertain.