EVIDENCE LIBRARY
Forensic interpretation of analytical methods, validation, interference, identification, and measurement limitations.
Sep 24, 2026
Brain tissue can be valuable when postmortem blood is unavailable or compromised, but brain–blood ratios and tissue concentrations require matrix-specific validation and cautious interpretation.
Read guideSep 24, 2026
A forensic toxicology guide to specimen collection, preservatives, containers, storage, transport, sampling site, and preanalytical records that can affect interpretation.
Read guideSep 23, 2026
Forensic guide to emerging ketamine- and PCP-like arylcyclohexylamines: positional isomers, LC-MS/MS, HRMS, GC-MS, NMR, and defensible identification.
Read guideSep 23, 2026
Medetomidine and xylazine can co-occur with fentanyl, but they differ analytically. Compare targets, metabolites, enantiomers, screening gaps, and interpretation.
Read guideSep 23, 2026
Case-focused checklist for reviewing a forensic toxicology validation package, method version, QC, raw data, calibration, interference, stability, and audit records.
Read guideSep 23, 2026
When manual peak re-integration is defensible in forensic toxicology, what audit trails should show, and how reviewers evaluate altered chromatographic results.
Read guideSep 23, 2026
How forensic LC-MS/MS methods test selectivity and interference, including coeluting drugs, metabolites, isomers, matrix effects, and false-positive risks.
Read guideSep 23, 2026
How processed-sample and autosampler stability affect LC-MS/MS forensic toxicology results, validation, reinjection, degradation, and case review.
Read guideSep 23, 2026
How to evaluate failed forensic toxicology quality control: batch rejection, analyte-specific impact, qualitative-only reporting, root-cause review, and case records.
Read guideSep 23, 2026
How stable-isotope internal standards improve forensic LC-MS/MS quantitation, where they fail, and what method validation and case review should examine.
Read guide